Barcode-Like Paper Sensor for Smartphone Diagnostics: An Application of Blood Typing
Liyun Guan, Junfei Tian, Rong Cao, Miaosi Li, Zhaoxiang Cai, Wei Shen
Abstract
This study introduced a barcode-like design into a paper-based blood typing device by integrating with smartphone-based technology. The concept of presenting a paper-based blood typing assay in a barcode-like pattern significantly enhanced the adaptability of the assay to the smartphone technology. The fabrication of this device involved the use of a printing technique to define hydrophilic bar channels which were, respectively, treated with Anti-A, -B, and -D antibodies. These channels were then used to perform blood typing assays by introducing a blood sample. Blood type can be visually identified from eluting lengths in bar channels. A smartphone-based analytical application was designed to read the bar channels, analogous to scanning a barcode, interpret this information, and then report results to users. The proposed paper-based blood typing device is rapidly read by smartphones and easy for the user to operate. We envisage that the adaptation of paper-based devices to the widely accepted smartphone technology will increase the capability of paper-based diagnostics with rapid assay result interpretation, data storage, and transmission.
BibTeX
@article{guan2014barcode,
title = {{Barcode-Like Paper Sensor for Smartphone Diagnostics: An Application of Blood Typing}},
author = {Liyun Guan and Junfei Tian and Rong Cao and Miaosi Li and Zhaoxiang Cai and Wei Shen},
journal = {Analytical Chemistry},
year = {2014},
doi = {10.1021/ac503300y}
}